PhD student position at Barazzuol lab


PhD – Biological mechanisms of radiotherapy-induced neurocognitive dysfunction


Department Radiation Oncology
Work location Groningen
Apply no later than 04 December 2017

Job description

Project description: When using radiotherapy in the treatment of brain tumours, damage to normal brain tissue is an unavoidable side effect. This can severely diminish the neurocognitive function of patients, especially in cases of paediatric brain tumours with a progressive average IQ decline of over 2 points per year. The underlying biological mechanisms of radiotherapy-induced neurocognitive dysfunction are not fully understood and, at present, there is no effective treatment. By using a combination of methodologies (ranging from in vivo imaging, behavioural tests, organotypic brain slices, primary cell culture, and proteomics), this PhD project aims to understand the underlying biological mechanisms of radiotherapy-induced neurocognitive dysfunction; and, to identify the structures of the brain that need to be spared from radiation during treatment in order to reduce neurotoxicity after radiotherapy.

What do we need

We are looking for an excellent, highly motivated candidate with strong laboratory skills and preferably with a background in neuroscience, biology, imaging or related fields.

The UMCG has a preventive Hepatitis B policy. You may be required to build up sufficient protection against Hepatitis B before you can be appointed. Vaccination is provided by the UMCG if necessary.

What do we offer

Your salary is € 2.279,- gross per month in the first year up to a maximum of € 2.919,- gross per month in the last year (PhD scale). In addition, the UMCG will offer you 8% holiday pay, an 8.3% end-of-year bonus and a development budget. The terms of employment comply with the Collective Labour Agreement for Medical Centers (CAO-UMC).
This project is funded by KWF and Alpe d’HuZes. The duration of the project is four years. Project starting date is 1st February 2018.

More information
For more information about this PhD position please contact:
Dr. Lara Barazzuol, Group Leader at the Dept. of Cell Biology, email: (please do not use for applications); telephone: +31 624 207 348.

Applying for a job
Please use the digital application form at the bottom of this page – only these will be processed.
You can apply until Monday 4 December 2017.
The application form requires:

  • A copy of your CV.
  • The names and contact information of two references (one of them preferably your advisor from your Master’s project or another research project).
  • A short motivation letter; please include why you are interested in this position and why you are a good candidate.

Immediately after sending the digital application form you will receive an email-confirmation with further information.

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